Supply Chain

Import / Export Department

Promedico has one of the largest and most highly skilled import-export departments of its kind. The department handles regular importation of pharmaceuticals, medical foods and infant foods, medical equipment, food supplements, narcotic drugs, cosmetics, and other products from all over the world by land and sea.

The department has extensive experience in import and export operations including compliance with Ministry of Health cold chain distribution requirements; release of goods from customs, the National Food Service, and Pharmaceutical Administration; and extensive knowledge in handling all aspects of the licensing requirements set down by the Standards Institute and the MoH. All operations conducted to create optimal fit between our partners’ requirements, the quality assurance of the distribution chain, and compliance with international standards (GMP).

The department is involved in importation from the moment goods are collected from the suppliers, to their release from customs and arrival in our warehouses. The department works in full cooperation with our suppliers, which help the department optimize inventory levels to match our needs and update according to the marketing and sales activities of our strategic partners.

 

Storage

Promedico’s storage site offers a diverse range of warehousing options for the storage of pharmaceuticals, cosmetics, food, and medical devices in compliance with MoH requirements and the most stringent quality standards.

The company’s warehouses are located on its 2.5 acres logistics center in Emeq Hefer, with a storage capacity of over 9,000 pallets. The center is strategically located to offer convenient access to the country’s main highways (Highway 6, Road No. 4, and the Coastal highway).

Warehouse and storage management based on a FEFO (First Expired First Out) policy, complies with cGMP/cGDP regulations and MoH requirements.

Promedico has two large cold storage rooms where vaccines and other sensitive pharmaceuticals are stored (in three temperature areas: 20-80,-200, -700), as well as a large vault for the storage of narcotic drugs. The warehouses are protected by alert-based security and temperature monitoring systems.

Promedico’s warehousing system also handles customer returns and conducts inventory integrity checks. Traceability is ensured by the company’s ERP system, which tracks lot numbers and expiry dates, to ensure consistency with on-hand inventory.

 

Distribution

Promedico makes over 1,000 deliveries a day to a diverse range of customers in almost 4,000 points of sale nationwide, including drugstore chains, private pharmacies, food and convenience store chains, HMOs, hospitals, senior living facilities, medical laboratories and research institutes, and home deliveries. Promedico maintains a high standard of customer service and commitment to delivery schedules in all distribution channels.

As an operator in the pharmaceuticals market, Promedico’s distribution conforms to cGMP/cGDP standards and MoH requirements. We use vehicles equipped with special refrigeration systems that maintain a temperature between 150-250 C and dedicated refrigeration containers for the distribution of sensitive products that require temperatures between 20– 80 C. The company’s temperature monitoring systems have been validated, and all vehicles are equipped with a GPS tracking system that allows the company to track temperatures in real time.

Promedico offers full traceability from a delivery’s arrival at the warehouse to its placement on the customer’s shelf.

Promedico’s distribution department also specializes in the distribution of radioactive substances, including their release from customs and rapid delivery to customers using dedicated vehicles.

 

Cold Chain Distribution

Promedico is Israel’s largest distributor of vaccines and biologicals, the sensitive nature of which requires special storage conditions (20-80 C), known as refrigeration.  Promedico’s cold chain distribution system ensures that these unique environmental conditions are maintained throughout the products’ entire lifetime. Since any breach in the cold chain can impair the quality and effectiveness of pharmaceuticals, cold chain distribution management is a complex task, especially when the distribution chain involves transportation in several countries and continents and entails product transfers using a variety of air and land transportation and shipping options.

The cold chain of biologicals begins in the manufacturing plant, where the manufacturer defines the required temperature range for the product, which determines various transportation and storage constraints. Many people mistakenly believe that overheating is the only problem for biologicals, but in effect, the cold chain’s greatest challenge is to prevent the temperature from dropping below the designated range and prevent the product from freezing.

This logistics challenge is complicated by the large number of product transfers and operators involved in the shipping process – transport from the factory to the airport, airport storage, loading, unloading, storage during customs release, transport by land to Promedico’s controlled refrigeration chamber, storage, and delivery to the customer. Each stage in the process creates an exposure risk that requires a complex risk management procedure. Extreme changes in outside temperatures also pose a challenge for the cold chain distribution system.

To ensure control of storage and transportation temperatures through the cold chain to Promedico’s warehouse, Promedico uses temperature-controlled containers (Eurotainers) or special refrigerated packages with independent power sources.

During the entire period of storage in Promedico’s warehouses, products that require refrigeration are stored in validated temperature-controlled chambers that ensure compliance with the manufacturer’s refrigeration requirements.

During delivery to customers, the products are transported inside a dedicated refrigerator in vehicles with a specially insulated, temperature-controlled cargo space. The refrigerator and cargo space undergo the same validation procedures as Promedico’s refrigeration chambers.

On the short distance from the refrigerated vehicle to the customer’s premises, the medicinal products are transported in insulated carrier bags containing refrigerated pads that maintain a temperature of 20-80 C. The refrigerated carriers have also undergone validation.

The most important elements in maintaining cold chain integrity are continuous communications, data transfer, and proper cold chain design from the manufacturing site to Promedico’s warehouses.

Critical information on the cold chain appears in item descriptions that are available both to the manufacturer and to Promedico. To confirm that the required temperature range is maintained, special sensors are attached to the inside and outside of the packages. These sensors monitor the temperature as the products flow through the distribution chain. When the product is entered into Promedico’s inventory, the sensors are detached from the package. The information on temperatures during transit, which is stored in the sensors’ memory, is forwarded to the QP, who confirms that the transit information is consistent with the manufacturer’s instructions before releasing each lot.

Due to Promedico’s high standards, uncompromising attention to cold chain integrity and the quality of services it provides to its customers in this field, Promedico has been selected by the MoH as its exclusive sub-contractor for vaccines distribution.

Promedico has also been designated by the MoH as the sole approved vendor for its national school health services, which includes storage of the vaccines, collection, preparation for distribution, collection of returns and relabeling.

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